Parramatta will travel down the road to Accor Stadium on Saturday night looking to put a six-point buffer on opponents South Sydney on the Telstra Premiership ladder.
The Eels lead the Rabbitohs by four competition points in sixth spot and if results go their way they could be in the top four by the end of the round.
South Sydney are producing a very inconsistent season and must find some form if they're going to make a dent in this year's competition after going down to the Dragons by 20 points in round 15.
Latrell Mitchell's return will help but overall Jason Demetriou's side can't rely on the fullback's comeback from a long-term hamstring injury to spark a resurgence.
The Rabbitohs have had the wood over Parramatta in recent games for an aggregate scoreline of 78-32 in 2021.
Parramatta will be expected to win - something they've struggled with at times against teams below them on the ladder - while the Rabbitohs are on the verge of slipping outside the top eight.
Sportsbet Betting preview: Rabbitohs v Eels
Rabbitohs: Latrell Mitchell is back from injury for his first game since round five, leaving Kodi Nikorima to revert to the bench. Damien Cook, Cameron Murray and Jai Arrow will all start after playing in Origin II. Taane Milne makes way for rookie Isaiah Tass in the centres, while Hame Sele gets the start at prop ahead of Mark Nicholls who will come off the interchange.
Eels: Marata Niukore will start at lock after Ryan Matterson dropped out of the team on Friday night. Prop Junior Paulo is good to go after playing 43 minutes in Origin II. The Eels' other representative players Dylan Brown, Waqa Blake and Maika Sivo will all play, with Tom Opacic joining the interchange in place of Matterson.
Match: Rabbitohs v Eels
Round 16 -
Fullback for Rabbitohs is number 1 Latrell MitchellFullback for Eels is number 1 Clinton Gutherson
Winger for Rabbitohs is number 2 Alex JohnstonWinger for Eels is number 2 Maika Sivo
Centre for Rabbitohs is number 4 Campbell GrahamCentre for Eels is number 3 Will Penisini
Centre for Rabbitohs is number 19 Isaiah TassCentre for Eels is number 4 Waqa Blake
Winger for Rabbitohs is number 5 Jaxson PauloWinger for Eels is number 5 Bailey Simonsson
Five-Eighth for Rabbitohs is number 6 Cody WalkerFive-Eighth for Eels is number 6 Dylan Brown
Halfback for Rabbitohs is number 7 Lachlan IliasHalfback for Eels is number 7 Mitchell Moses
Prop for Rabbitohs is number 8 Tevita TatolaProp for Eels is number 8 Reagan Campbell-Gillard
Hooker for Rabbitohs is number 9 Damien CookHooker for Eels is number 9 Reed Mahoney
Prop for Rabbitohs is number 17 Hame SeleProp for Eels is number 10 Junior Paulo
2nd Row for Rabbitohs is number 11 Keaon Koloamatangi2nd Row for Eels is number 11 Shaun Lane
2nd Row for Rabbitohs is number 12 Jai Arrow2nd Row for Eels is number 12 Isaiah Papali'i
Lock for Rabbitohs is number 13 Cameron MurrayLock for Eels is number 15 Marata Niukore
Interchange for Rabbitohs is number 10 Mark NichollsInterchange for Eels is number 14 Makahesi Makatoa
Interchange for Rabbitohs is number 14 Kodi NikorimaInterchange for Eels is number 16 Oregon Kaufusi
Interchange for Rabbitohs is number 15 Thomas BurgessInterchange for Eels is number 17 Ky Rodwell
Interchange for Rabbitohs is number 16 Siliva HaviliInterchange for Eels is number 18 Tom Opacic
Replacement for Rabbitohs is number 3 Taane MilneReplacement for Eels is number 19 Jake Arthur
- Referee: Ben Cummins
- Touch Judge: Drew Oultram
- Touch Judge: Todd Smith
- Senior Review Official: Chris Butler
Cody Walker v Dylan Brown: Two playmakers at different stages of their career but vitally important to their respective sides. Walker has been on the end of some criticism for his yo-yo form to coincide with the Rabbitohs' inconsistency this year but there's no doubting when he's on the side responds. It's a similiar case for Brown, who has taken his game to another level this year and acts as the perfect foil for Mitchell Moses. Coming off an international debut for the Kiwis, Brown will be looking to take that experience into this weekend's fixture.
Parramatta have the best completion rate in the NRL alongside the Panthers. It's no surprise below both western Sydney clubs are the Broncos, Storm and Cowboys, who are all in the top six as it stands. South Sydney are ranked last in this area with 72% on average. There was once a time in recent years gone by that completion rates weren't everything but this year's trends towards hold the ball and you'll win the game.
Match: Rabbitohs v Eels
Round 16 -
Venue: Accor Stadium, Sydney