The Round 14 clash sees the Eels continuing their push for a top four finish, while the Dragons are playing to keep their finals hopes alive.
Here are five things you need to know about the meet.
Eels nudging top ladder spot
The Eels are hovering just below The Panthers and will need to win their final seven games of the normal rounds to secure top spot.
With an 11-2 record, the Blue and Gold are in the right position to claim top spot.
Eels back home at Bankwest Stadium
The Blue and Gold will happily run out onto their fortress on Friday night, back where they’re most comfortable.
With two gritty wins away from home behind them, the Eels will be looking to emulate their golden start to the 2020 NRL Premiership.
Dragons coach exits
The Dragons will need to shake off the distraction of the last week, after their coach Paul McGregor resigned ahead of the game.
However he will remain at the helm for one last time in Round 14.
The Red V will be put to the test to see if they get one last win for their departing coach?
The Eels lead the comp for offloads with 192 and boast 59 more than the second place team.
The Blue and Gold also lead the way for run metres with 24, 619 metres under their belt.
The Dragons are third for set completions, sitting at 80 per cent.
They also lead the way for kick metres, with 8708 metres.
Ryan Matterson will return from concussion in the back row with Marata Niukore dropping to the bench and Andrew Davey to 18th man.
The Eels have won nine of their past 10 games against the Dragons.
The Dragons welcome back Corey Norman to five-eighth, shifting Ben Hunt to hooker and Cam McInnes to lock with the suspended Jackson Ford out.
Tyrell Fuimaono starts in the back row following a shoulder injury to Tariq Sims.
Trent Merrin is also out with Korbin Sims and Jacob Host in the side.